Field Notes

Observations are made along the way.
Thoughts that are not planned, but rather emerge spontaneously.

The Field Notes consist of records from the world of NATURFACTOR® – about skin, care and the rhythm that connects both.

Tachyphylaxis bei Retinoid-Dauertherapie – Pausierungsrhythmen vs. Dosismodulation

Tachyphylaxis in Retinoid Maintenance Therapy – Pulsed Dosing vs. Dose Modulation

Why the Skin Reacts to Long-Term Retinoid Therapy with Decreased Efficacy – and Which Protocol Strategies Can Maintain Receptor Sensitivity in the Long Term.

Read more: Tachyphylaxis in Retinoid Maintenance Therapy – Pulsed Dosing vs. Dose Modulation
Wechseljahre-Haut: Estrogen-Kollaps und Lipid-Rekompensation unter Barriere-Dekompensation

Menopause skin: Estrogen collapse and lipid recompensation amid barrier decompensation

When estrogen levels drop, lipid synthesis, the collagen matrix, and barrier function all come under pressure simultaneously. What happens biochemically—and which skincare logic science suggests.

Read more: Menopause skin: Estrogen collapse and lipid recompensation amid barrier decompensation
Menopausal Skin Transition – Kollagen-Dekompensation und Lipid-Insuffizienz im Alterungsprozess

Menopausal Skin Transition – Collagen Decompensation and Lipid Insufficiency in the Aging Process

Menopause profoundly changes the collagen structure and lipid barrier of the skin. What science knows about this transitional phase – and what that means for...

Read more: Menopausal Skin Transition – Collagen Decompensation and Lipid Insufficiency in the Aging Process
Algenbasierte Bioretinol-Alternativen: Marine Wirkstoffe als sanfte Antwort auf synthetische Retinoide

Algae-Based Bioretinol Alternatives: Marine Active Ingredients as a Gentle Answer to Synthetic Retinoids

Fucoxanthin, fucoidan, and marine carotenoid complexes are gaining attention in skin research as more tolerable supplements to synthetic retinoids. What the literature says about algae-based...

Read more: Algae-Based Bioretinol Alternatives: Marine Active Ingredients as a Gentle Answer to Synthetic Retinoids
NAD⁺, Zellenergie & Mitochondrial Skincare: Was die Forschung über zelluläre Hautalterung sagt

NAD⁺, Cell Energy & Mitochondrial Skincare: What research says about cellular skin aging

NAD⁺ is considered a central coenzyme of cellular energy – and its age-dependent decline is increasingly linked to cutaneous aging in scientific research. What mitochondrial...

Read more: NAD⁺, Cell Energy & Mitochondrial Skincare: What research says about cellular skin aging
Mikroverkapselte Retinolformen – 35 % Potenzsteigerung bei verbesserter Verträglichkeit

Microencapsulated Retinol Forms – 35% Potency Boost with Improved Tolerability

How nanoscopic delivery systems can increase retinol bioavailability by up to 35%—and why formulation is more critical than mere concentration.

Read more: Microencapsulated Retinol Forms – 35% Potency Boost with Improved Tolerability
Radiofrequenz-Microneedling: Klinik-Systeme, Heimgeräte & was die Wissenschaft sagt

Radiofrequency Microneedling: Clinic Systems, Home Devices & What the Science Says

RF microneedling is one of the most thoroughly researched non-invasive skin technologies — but the difference between clinical systems and consumer devices is significant. What...

Read more: Radiofrequency Microneedling: Clinic Systems, Home Devices & What the Science Says
GLP-1-Gewichtsverlust & Hautpflege: Restaurative Formeln für metabolisch veränderte Haut

GLP-1 Weight Loss & Skincare: Restorative Formulas for Metabolically-Shifted Skin

GLP-1 agonists like semaglutide don't just change weight — they leave visible marks on the skin's appearance. What barrier research and chrono-care can do for...

Read more: GLP-1 Weight Loss & Skincare: Restorative Formulas for Metabolically-Shifted Skin
PDRN – Lachsspermien-Polynukleotide in der Hautpflege: Wirkmechanismen, Formulierungsformen & Anwendung

PDRN – Salmon Sperm Polynucleotides in Skincare: Mechanisms of Action, Formulation Types & Application

PDRN – polynucleotides derived from salmon sperm – is considered one of the most scientifically interesting bioactive ingredients in modern skincare. What's behind this molecule,...

Read more: PDRN – Salmon Sperm Polynucleotides in Skincare: Mechanisms of Action, Formulation Types & Application

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